Pamidronate disodium
Trade Name:
Aredia
Type of Drug:
Pamidronate disodium belongs to a specific class of calcium-lowering agents called biphosphonates used to treat hypercalcemia (high calcium level in the blood).
How Drug Works:
Pamidronate disodium stops bone breakdown, so calcium is not released from the bones into the blood. It is used to treat bone metastases from breast cancer.
How Drug Is Given:
Pamidronate disodium is given by injection in a vein over 2 to 4 hours. The dose is the same for all adults. You may also get fluids by vein to help your kidneys make urine.
Read the following information. If you do not understand it or if any of it causes you special concern, check with your doctor.
Before taking this drug, tell your doctor if you are taking any other prescription or over-the-counter drugs, including vitamins and herbals.
Should I avoid any other medicines, foods, alcohol, and/or activities?
Your prescription and nonprescription medicines may interact with other drugs, causing harm. Certain foods or alcohol can also interact with drug products. Never begin taking a new medicine"prescription or nonprescription"without asking your doctor or nurse if it will interact with alcohol, food, or other medicines. Some drug products can cause drowsiness and affect activities such as driving.
Tell all the doctors, dentists, and pharmacists you visit that you are taking this drug.
  • Most of the following side effects probably will not occur.
  • Your doctor or nurse will want to discuss specific care instructions with you.
  • They can help you understand these side effects and help you deal with them.
Side Effects:
More Common Side Effects
  • Fever lasting for a short time 24 to 48 hours after infusion
  • Pain at place of injection
  • Irritation of vein used for giving the drug
Less Common Side Effects
  • Nausea
  • Constipation
  • Decreased appetite
Rare Side Effects
  • Vomiting
  • Abdominal discomfort
Other side effects not listed above can also occur in some patients. Tell your doctor or nurse if you develop any problems.
FDA Approval: Yes