CHCWM – Cancer & Hematology Centers of West Michigan

ALPN-202-NEON-1 (Alpine Immune Sciences)

ALPN-202 – NEON-1 (Alpine Immune Sciences)

Description:  An open-Label Study of ALPN-202 In Subjects With Advanced Malignancies (NEON-1)

 Mechanism of Action: Inhibits PDL1 and CTLA4, engages CD28 co-stimulator.

Target Patient Population: Currently in expansion for Melanoma, Renal cell  and PDL1 positive cancers only

Study Design: Study drug is administered IV every 1 or 3 weeks