CHCWM – Cancer & Hematology Centers of West Michigan

ALPN-202-NEON-2 (Alpine Immune Sciences)

ALPN-202 – NEON-2 (Alpine Immune Sciences)

 Description:  An open-Label Study of ALPN-202 Combined With PD-1 Inhibition In Subjects With Advanced Malignancies (NEON-2)

Mechanism of Action: Inhibits PDL1 and CTLA4, engages CD28 co-stimulator in combination with Pembrolizumab.

Target Patient Population:.  All solid tumors

Study Design: Study drug is administered IV every 1 or 3 weeks