CHC – The Cancer & Hematology Centers

TWT-101 (Treadwell Therapeutics, Inc.)

TWT-101 (Treadwell Therapeutics, Inc.)

Description:  A First In-Human, Phase I/II Study of CFI-402411, Hematopoietic Progenitor Inase-1 (HPK1) Inhibitor, As A Single Agent and In Combination With Pembrolizumab In Subjects With Advanced Solid Malignancies

 

Target Patient Population:   Non small cell lung cancer, Small cell lung cancer, Squamous cancers of Head and Neck, Anal or Skin, Urothelial, Renal Cell, Triple Negative Breast , Endometrial, Cervical, Gastroesophageal, Hepatocellular or any MSI-H cancer.

Study Design:  Drug is given orally daily.